Ahmet-Dedeler

Ahmet-Dedeler/celiac-trial-sim

Could these celiac trials have detected their drugs? TAK-101 prevented 71% of gluten injury and was written up as a failure. At 13 patients per arm it needed 95%. Endpoint noise is not constant: SD = 0.40 + 0.30 × injury.

2 good first / help-wanted issues · Python · last activity Oct 4, 2026

biostatistics celiac-disease clinical-trials collaborate data-science learn meta-research python reproducible-research statistical-power student-project
2 Open Issues Need Help Last updated: Oct 4, 2026

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Ahmet-Dedeler/celiac-trial-sim
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Could these celiac trials have detected their drugs? TAK-101 prevented 71% of gluten injury and was written up as a failure. At 13 patients per arm it needed 95%. Endpoint noise is not constant: SD = 0.40 + 0.30 × injury.

Python
#biostatistics#celiac-disease#clinical-trials#collaborate#data-science#learn#meta-research#python#reproducible-research#statistical-power#student-project
Ahmet-Dedeler/celiac-trial-sim
0

Could these celiac trials have detected their drugs? TAK-101 prevented 71% of gluten injury and was written up as a failure. At 13 patients per arm it needed 95%. Endpoint noise is not constant: SD = 0.40 + 0.30 × injury.

Python
#biostatistics#celiac-disease#clinical-trials#collaborate#data-science#learn#meta-research#python#reproducible-research#statistical-power#student-project