3 Open Issues Need Help Last updated: Jun 17, 2025

Open Issues Need Help

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Bioinformatics RNA Sequencing

AI Summary: The task requires troubleshooting an RNA-seq fusion gene analysis issue within the nf-core framework. This involves understanding the sci_wiz RNA-seq workflow, reproducing the bug using provided inputs, comparing the actual output to the expected output, and providing debugging information including screenshots and system details. The issue report needs to be detailed enough for developers to understand and resolve the problem.

Complexity: 4/5
bug enhancement good first issue question

SCI_WIZ: Scotland institute(CRUK) workflow wizard

Python
Bioinformatics RNA Sequencing

AI Summary: The task requires debugging an RNA-Seq data preprocessing workflow (sci_wiz) that experiences issues when handling a large number of input files and processes. The debugging needs to identify the source of the error, likely related to process forking or file handling limitations, and implement a solution to manage input data more efficiently. This involves analyzing the workflow's code, understanding its interaction with the operating system and potentially adjusting parameters to optimize resource usage.

Complexity: 4/5
bug enhancement good first issue question

SCI_WIZ: Scotland institute(CRUK) workflow wizard

Python
Bioinformatics RNA Sequencing

AI Summary: Integrate FastQ Screen into the sci_wiz RNA-Seq workflow to detect potential contamination in FastQ files as part of the quality control (QC) process. This involves adding FastQ Screen to the existing Nextflow pipeline, handling its output, and potentially updating the documentation and configuration.

Complexity: 3/5
enhancement good first issue question

SCI_WIZ: Scotland institute(CRUK) workflow wizard

Python