Software for painlessly estimating average nucleotide diversity within and between populations

9 Open Issues Need Help Last updated: Aug 10, 2026

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Software for painlessly estimating average nucleotide diversity within and between populations

Python

Software for painlessly estimating average nucleotide diversity within and between populations

Python

Software for painlessly estimating average nucleotide diversity within and between populations

Python

Software for painlessly estimating average nucleotide diversity within and between populations

Python

Software for painlessly estimating average nucleotide diversity within and between populations

Python

Software for painlessly estimating average nucleotide diversity within and between populations

Python

AI Summary: A user updated `pixy` from beta 8 to beta 12 and observed a significant reduction in the reported number of SNPs (`no_snps`) in the Fst output, even when processing a biallelic VCF without using the new multiallelic SNP parameter. This indicates a potential regression or an undocumented change in SNP counting or filtering logic between the two beta versions, leading to different results for identical inputs.

Complexity: 3/5
help wanted

Software for painlessly estimating average nucleotide diversity within and between populations

Python

AI Summary: The user is attempting to run `pixy` v2.0 on a VCF containing mixed-ploidy individuals (haploid males, diploid females) on the X chromosome. `pixy` infers a single ploidy and advises splitting the VCF, leading the user to question if it's possible to analyze such data in a single run or if separate analyses for each ploidy group are required. The issue seeks clarification on `pixy`'s current capabilities regarding variable ploidy within a single chromosome analysis.

Complexity: 2/5
help wanted

Software for painlessly estimating average nucleotide diversity within and between populations

Python

AI Summary: A user encountered a `ModuleNotFoundError` for `typing_extensions` when installing `pixy 2.0.0.beta12` on Python 3.11. This indicates that `typing_extensions` is a missing dependency for the `pixy` package. The suggested fix is to add `typing-extensions` to the project's requirements.

Complexity: 1/5
help wanted

Software for painlessly estimating average nucleotide diversity within and between populations

Python