lanl

lanl/PyBNF

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

5 good first / help-wanted issues · Python · last activity Aug 21, 2026

25 stars 20 forks 25 watchers Python Other
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5 Open Issues Need Help Last updated: Aug 21, 2026

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dev/PUNCHLIST.md is cited by pyproject.toml and tests/README_integration.md but is gitignored and never committed, making two lint ignores unauditable about 1 month ago
good first issue minor
lanl/PyBNF
25

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

Python
Two logging calls have a %s with no argument, so they log the literal placeholder (DREAM drops the out-of-bounds parameter name) about 1 month ago
bug good first issue minor
lanl/PyBNF
25

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

Python
The contributor setup notes describe a workaround that may no longer be needed 2 months ago
enhancement good first issue
lanl/PyBNF
25

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

Python
Temporary dask directories are never removed because dask changed the name 2 months ago
bug good first issue
lanl/PyBNF
25

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

Python
Use scipy.stats functions for defining distributions 7 months ago
enhancement good first issue high priority
lanl/PyBNF
25

An application for parameterization of biological models available in SBML and BNGL formats. Features include parallelization, metaheuristic optimization algorithms, and an adaptive Markov chain Monte Carlo (MCMC) sampling algorithm.

Python