monarch-initiative/dismech

corticospinal_tract_axonopathy module notes call GJC2 "SPG42" — it is SPG44 about 1 hour ago

bug good first issue curation low_effort

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Priority diseases to curate (huge EPIC, CZI) 1 day ago

enhancement help wanted

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Upstream MONDO: Fanconi anemia classification problems (FA-A is a skeletal dysplasia, FA is an inborn error of metabolism) 1 day ago

bug help wanted discussion mondo-upstream

monarch-initiative/dismech

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CLAUDE.md's pre-PR gate list omits four gates that `just qc` runs 1 day ago

documentation good first issue technical-debt low_effort

monarch-initiative/dismech

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Bind the numbered MONDO IDs folded by PR #9855 as subtype_term / narrowMatch mappings so seed-stubs cannot re-nominate them 1 day ago

help wanted curation medium_effort

monarch-initiative/dismech

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Stub queue: telomere biology disorder stubs (dyskeratosis congenita, PFBMFT series, telomere syndrome) need one coordinated ruling 3 days ago

help wanted curation high_effort discussion

monarch-initiative/dismech

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Stub queue: ~30 broad-category stubs need a grouping vs out-of-scope ruling 3 days ago

help wanted curation high_effort discussion

monarch-initiative/dismech

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Stub queue: COXPD (25 stubs) and nuclear complex I/III deficiency (33 stubs) — collapse, group, or keep per-number? 3 days ago

help wanted curation high_effort discussion

monarch-initiative/dismech

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Stub queue: 139 DFNA/DFNB numbered hearing-loss stubs — collapse to two lumped stubs, or keep per-locus? 3 days ago

help wanted question curation high_effort discussion

monarch-initiative/dismech

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Stub queue: 31 numbered cardiomyopathy stubs sit under existing Familial_Dilated/Hypertrophic_Cardiomyopathy groupings 3 days ago

help wanted curation high_effort

monarch-initiative/dismech

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Stub queue: small on-the-fence numbered families left undecided by the lump/split review 3 days ago

help wanted curation low-priority high_effort discussion

monarch-initiative/dismech

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Bracket stripping silently truncates snippets, and the ellipsis workaround is undocumented 3 days ago

documentation enhancement good first issue medium_effort tooling

monarch-initiative/dismech

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preflight-dr has no Named Entity Confusion check for non-Mendelian diseases 3 days ago

documentation enhancement good first issue low-priority tooling

monarch-initiative/dismech

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`preflight-dr` reports a disease's own effector gene as a "rival gene" 3 days ago

bug good first issue low-priority tooling

monarch-initiative/dismech

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Scope decision: where does purely computational NAM evidence (virtual imaging trials) belong? 3 days ago

enhancement help wanted question high_effort discussion

monarch-initiative/dismech

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help wanted curation knowledge_gaps mondo discussion

monarch-initiative/dismech

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test_grouping_member_foreign_keys takes ~23s per grouping file because _disease_names() is not cached 8 days ago

good first issue infra test low-priority technical-debt low_effort

monarch-initiative/dismech

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[kgap-scan:scope] Neurodegenerative Diseases: Autophagy-Senescence-Inflammasome (ASI) axis as unified cross-disease mechanism 11 days ago

help wanted curation high_effort knowledge_gaps

monarch-initiative/dismech

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Schema gap: OnsetEnum has no generic ADULT (HP:0003581) value — the HPO parent of its three adult buckets 20 days ago

enhancement good first issue schema low-priority

monarch-initiative/dismech

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Cystic_Fibrosis.yaml: HP:0410017 is "Otitis externa", not "Abnormal sweat electrolyte concentration" 29 days ago

bug good first issue curation low_effort

monarch-initiative/dismech

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Enumerate cases where a dismech entry should not have a corresponding Mondo ID about 1 month ago

help wanted question curation

monarch-initiative/dismech

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[lit-scan:new] Cole-Carpenter Syndrome: P4HB Y393C model and therapeutic drug screening about 2 months ago

help wanted infra curation high_effort

monarch-initiative/dismech

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The dismech-entry → MONDO-term relationship should be 1:1 about 2 months ago

help wanted question curation curation hackathon

monarch-initiative/dismech

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De-duplicate the two X-ALD entries (cerebral ALD is over-split from the ABCD1 umbrella) about 2 months ago

enhancement help wanted curation high_effort

monarch-initiative/dismech

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Clean up ~335 pre-existing YAML folded-scalar compound-word splits in kb/ 2 months ago

good first issue low_effort

monarch-initiative/dismech

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Curate dyslexia 3 months ago

enhancement good first issue curation

monarch-initiative/dismech

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Add congenital fibrinogen disorder entries and ER storage disease module 3 months ago

enhancement help wanted curation

monarch-initiative/dismech

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Add `biomarker_term` bindings to SCDS biochemical entries (calcium, vitamin D) 4 months ago

enhancement good first issue curation

monarch-initiative/dismech

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Add dismech entry: Morquio syndrome 5 months ago

enhancement help wanted

monarch-initiative/dismech

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Add dismech entry: Sandhoff disease 5 months ago

enhancement help wanted

monarch-initiative/dismech

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Re-review needed: PR #876 — compliance PR merged with agent-submitted approval 5 months ago

help wanted invalid

monarch-initiative/dismech

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Re-review needed: PR #875 — compliance PR merged with agent-submitted approval 5 months ago

help wanted invalid

monarch-initiative/dismech

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Re-review needed: PR #873 — compliance PR merged with agent-submitted approval 5 months ago

bug help wanted infra

monarch-initiative/dismech

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Review how treatment procedures are used in Dismech 5 months ago

enhancement good first issue

monarch-initiative/dismech

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Re-review needed: PR #844 ([claude] feat/skel-new-sd-eds) — merged without proper review 5 months ago

help wanted invalid

monarch-initiative/dismech

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Re-review needed: PR #593 (Add mechanistic hypotheses to Huntington's Disease) — merged without proper review 5 months ago

help wanted invalid

monarch-initiative/dismech

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Re-review needed: PR #714 (🤖 Weekly Compliance Fixes - Gastric Cancer H. pylori Associated (2026-03-20)) — merged without proper review 5 months ago

bug help wanted infra

monarch-initiative/dismech

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Re-review needed: PR #611 (Add comprehensive Multiple System Atrophy curation) — merged without proper review 5 months ago

help wanted invalid

monarch-initiative/dismech

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Re-review needed: PR #849 (🤖 Weekly Compliance Fixes (2026-04-03): Metastatic Gastric Cancer) — merged without proper review 5 months ago

bug help wanted infra

monarch-initiative/dismech

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Re-review needed: PR #847 (🤖 Weekly Compliance Fixes (2026-04-03): H3 K27-Altered Diffuse Midline Glioma) — merged without proper review 5 months ago

bug help wanted infra

monarch-initiative/dismech

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Add internal links between disorder pages 7 months ago

documentation enhancement good first issue

monarch-initiative/dismech

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Editorial: Add therapeutic_agent CHEBI qualifiers to pharmacotherapy treatments 8 months ago

documentation enhancement good first issue

monarch-initiative/dismech

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