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Nextflow good first issues

24 open Nextflow issues currently match the default 10+ star filter. Scored difficulty: 5,947 at 1/5, 8,791 at 2/5, 12,710 at 3/5, 12,148 at 4/5, 859 at 5/5. This hub uses the same feed as the homepage, limited to repositories whose GitHub language is Nextflow.

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Active filters:Language: Nextflow • Stars: 10+ Stars
Filters trigger API requests for better performance

Showing 30 of 24 opportunities to contribute from the last 98 days

AI Summary: This issue proposes adding a new visualization to the MultiQC report that displays taxonomic classifications of contigs. The goal is to have a stacked bar chart similar to existing read-level classifications, ideally incorporating a metric for completeness.

Complexity:3/5
enhancementhelp wantedpriority

A nf-core pipeline for untargeted whole genome reconstruction with iSNV detection from metagenomic samples.

Nextflow
#epidemiology#fastq#nextflow#nf-core#ngs#pipeline#viral-metagenomics#virology#virus-genomes#workflow

AI Summary: This issue proposes adding support for Metabuli, a tool that classifies metagenomic reads by comparing them to reference genomes using both amino acid and nucleotide comparisons. The goal is to integrate this functionality into the existing project.

Complexity:3/5
enhancementhelp wanted

A nf-core pipeline for untargeted whole genome reconstruction with iSNV detection from metagenomic samples.

Nextflow
#epidemiology#fastq#nextflow#nf-core#ngs#pipeline#viral-metagenomics#virology#virus-genomes#workflow

AI Summary: This issue requires updating nf-core modules used in nf-core/eager to include a 'versions' topic. Some modules can be updated automatically using `nf-core modules update`, while others may require manual intervention or upstream fixes.

Complexity:2/5
help wantedneeds upstream fixDSL2

A fully reproducible and state-of-the-art ancient DNA analysis pipeline

Nextflow
#adna#ancient-dna-analysis#ancientdna#bioinformatics#genome#metagenomics#nextflow#nf-core#pathogen-genomics#pipeline#population-genetics#workflow

AI Summary: The user is inquiring if the nf-core/smrnaseq pipeline supports the analysis of small RNA biotypes beyond miRNAs, such as piRNAs, tRNAs, and rRNAs. They are seeking guidance on how to perform such analyses if supported, or recommendations for alternative workflows if not.

Complexity:3/5
enhancementhelp wantedquestiondocumentation

A small-RNA sequencing analysis pipeline

Nextflow
#nextflow#nf-core#pipeline#small-rna#smrna-seq#workflow
help wanted

Nextflow DSL2 pipeline to generate data for a BlobToolKit analysis. This workflow is part of the Tree of Life production suite.

Nextflow
#blobtools#decontamination#genomehubs#genomics#nextflow#pipeline#workflow

AI Summary: This issue proposes packaging additional functions from the blobtoolkit library, specifically `blobtoolkit/blobdir` and `blobtoolkit/windowstats`, as individual nf-core modules. This would allow users to leverage these specific tools within their own Nextflow pipelines without needing to run the entire sanger-tol pipeline.

Complexity:2/5
enhancementgood first issuehelp wantedmaintain

Nextflow DSL2 pipeline to generate data for a BlobToolKit analysis. This workflow is part of the Tree of Life production suite.

Nextflow
#blobtools#decontamination#genomehubs#genomics#nextflow#pipeline#workflow
help wantedgood first issue

Nextflow DSL2 pipeline to align short and long reads to genome assembly. This workflow is part of the Tree of Life production suite.

Nextflow
#genomics#nextflow#pipeline#read-alignment

AI Summary: The user wants to enable the nf-co2footprint plugin by default in machine configuration profiles. A test is currently preventing this, citing that plugin definitions are only allowed at the top-most config scope. The user is questioning the reasoning behind this restriction and seeking a way to include plugins in their desired configuration.

Complexity:3/5
enhancementhelp wantedquestion

Config files used to define parameters specific to compute environments at different Institutions

Nextflow
#bioinformatics#configuration#nextflow#nf-core#pipelines#workflows

AI Summary: This issue proposes to standardize the naming convention of normalized variant files generated by different tools. Currently, one tool outputs files with a '.normalised.vcf.gz' suffix, while another uses '.norm.vcf.gz'. The suggested solution is to adjust the configuration of the latter tool to match the former's naming.

Complexity:2/5
enhancementgood first issue

Assembly and intrahost/low-frequency variant calling for viral samples

Nextflow
#amplicon#artic#assembly#covid-19#covid19#illumina#long-read-sequencing#metagenomics#nanopore#nextflow#nf-core#ont#oxford-nanopore#pipeline#sars-cov-2#variant-calling#viral#virus#workflow

AI Summary: This issue is part 5 of a larger effort to adopt topic channels across all nf-core modules. It lists a significant number of modules that need to be updated to use topic channels, indicating a systematic refactoring task. The goal is to improve the organization and maintainability of the nf-core modules.

Complexity:4/5
good first issue

Repository to host tool-specific module files for the Nextflow DSL2 community!

Nextflow
#dsl2#modules#nextflow#nf-core#nf-test#pipelines#workflows

AI Summary: This feature request aims to expand the capabilities of scverse-related modules within the nf-core/modules repository. Currently, these modules only support the h5ad file format for input and output. The user proposes adding support for the zarr file format, which has seen significant improvements in recent development.

Complexity:3/5
enhancementgood first issue

Repository to host tool-specific module files for the Nextflow DSL2 community!

Nextflow
#dsl2#modules#nextflow#nf-core#nf-test#pipelines#workflows

AI Summary: This issue reports a discrepancy in minimum quality filtering between the IVAR and mpileup masking steps within the viralrecon pipeline. The user points to specific configuration lines where these minimum quality values are set, suggesting they should be unified for consistent masking. This is a bug that could lead to inconsistent variant calling or masking results.

Complexity:2/5
buggood first issue

Assembly and intrahost/low-frequency variant calling for viral samples

Nextflow
#amplicon#artic#assembly#covid-19#covid19#illumina#long-read-sequencing#metagenomics#nanopore#nextflow#nf-core#ont#oxford-nanopore#pipeline#sars-cov-2#variant-calling#viral#virus#workflow

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